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A phase II trial of docetaxel and erlotinib as first-line therapy for elderly patients with androgen-independent prostate cancer

✍ Scribed by Mitchell Gross; Celestia Higano; Allan Pantuck; Olga Castellanos; Erica Green; Koo Nguyen; David B Agus

Book ID: 115011020
Publisher: BioMed Central
Year: 2007
Tongue: English
Weight: 278 KB
Volume: 7
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-7-142

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## Abstract ## BACKGROUND. The addition of diethylstilbestrol to docetaxel modified tubulin composition and improved the response of prostate cancer to chemotherapy in preclinical models. An attempt was made to recapitulate the observations in a clinical trial. ## METHODS. Twenty‐nine patients w