## Background: Patients with metastatic nonsmall cell lung carcinoma (nsclc) usually have a poor prognosis. a chemotherapy regimen containing cisplatin is commonly used for symptom palliation. echinomycin is a potent bifunctional intercalator of double-strand dna; trimetrexate is a new derivative o
A Phase II trial of cisplatin plus WR-2721 (amifostine) for metastatic breast carcinoma : An Eastern Cooperative Oncology Group Study (E8188)
β Scribed by William J. Gradishar; Patricia Stephenson; Donna J. Glover; Donna S. Neuberg; Melvin R. Moore; Harold E. Windschitl; Ira Piel; Martin D. Abeloff
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 77 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. A Phase II study was conducted to evaluate the response, duration of response, and duration of survival of patients with measurable gastric carcinoma treated with trimetrexate (TMTX) who had not had prior chemotherapy. ## METHODS. Thirty-three patients with unresectable or metast
The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of the National Cancer Institute.
Chemotherapy has a limited impact on adenocarcinoma of the stomach. Although biochemical modulation of 5-fluorouracil (5-FU) by leucovorin (LV) and interferon-β£ (IFN-β£) has improved the outcomes of patients with metastatic colorectal carcinoma compared with 5-FU alone, this approach has not been ext