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A phase II study of temozolomide in hormone-refractory prostate cancer

✍ Scribed by Jérôme P. van Brussel; Martijn B. Busstra; Margreet S. Lang; Tilly Catsburg; Fritz H. Schröder; Gerald H. Mickisch


Publisher
Springer
Year
2000
Tongue
English
Weight
71 KB
Volume
45
Category
Article
ISSN
0344-5704

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To determine the efficacy of recombinant human leukocyte alpha-interferon (IFL-RA) in advanced hormone-refractory prostate cancer, the authors treated 40 patients with IFL-RA administered intramuscularly at a dose of 10 x 10' U/m2 three times weekly. Toxicity was substantial and necessitated at leas