A phase II study of ifosfamide in the treatment of recurrent sarcomas in young people
β Scribed by Ian Magrath; John Sandlund; Anthony Raynor; Steven Rosenberg; Vivian Arasi; James Miser
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 383 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0344-5704
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The purpose of this study was to evaluate the antitumor activity and tolerability of ifosfamide (IFO) at a dose of 3 g/m2, given on 2 consecutive days every 2 weeks, in advanced Wilms' tumor patients in whom conventional therapy had failed. Mesna and hyperhydration were concomitantly given to minimi
Background. The prognosis for children with recurrent or resistant malignant solid tumors remains dismal. More effective rescue therapy is needed for these children. Methods. Between August 1987 and November 1990, 311 children with recurrent or resistant malignant solid tumors were treated by inves