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A phase I trial of perillyl alcohol administered four times daily for 14

✍ Scribed by Howard H. Bailey; George Wilding; Kendra D. Tutsch; Rhoda Z. Arzoomanian; Dona Alberti; Chris Feierabend; Kris Simon; Rebecca Marnocha; Sarah A. Holstein; Jan Stewart; Kriste A. Lewis; Raymond J. Hohl


Publisher
Springer
Year
2004
Tongue
English
Weight
260 KB
Volume
54
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND The epothilones are a novel class of microtubule‐stabilizing agents. Ixabepilone (BMS‐247550; NSC 710428) is a semisynthetic analog of the natural product epothilone B. The authors conducted a Phase I study by administering ixabepilone to patients as a 1‐hour intravenous