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A phase I trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors

✍ Scribed by Suzanne F. Jones, Jeffrey R. Infante…

Book ID
120776502
Publisher
Springer
Year
2012
Tongue
English
Weight
167 KB
Volume
70
Category
Article
ISSN
0344-5704

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A Phase I and feasibility study of combined docetaxel (D) plus paclitaxel (P) was undertaken to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) for each analogue delivered concomitantly on a weekly schedule. ## METHODS. Patients were accrued in 3-6 patient cohorts to P