A phase I trial of gemcitabine administered as a 96-h continuous intravenous infusion in patients with advanced carcinoma and lymphoma
β Scribed by Lakshmi Rajdev; Gary Goldberg; Una Hopkins; Joseph A. Sparano
- Book ID
- 111641091
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Weight
- 330 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1357-0560
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π SIMILAR VOLUMES
Eighteen patients with advanced malignancies refractory to other forms of treatment were given dactinomycin (Act D) as continuous intravenous infusions. Their median age was 51 years (range, 36-67); their median performance status was 50 (range, 40-90) on the Karnofsky scale. Act D was administered
## Abstract ## BACKGROUND There is no effective systemic therapy for patients with hepatocellular carcinoma. A recent trial reported a moderate antitumor activity for gemcitabine among Asian patients with advanced hepatocellular carcinoma. This led to our examination of the efficacy and tolerabili