A bioassay was developed to assess P-glycoprotein (P-gp) function of peripheral blood natural killer (NK) cells and AML blasts during zosuquidar infusion. Cells were incubated with the fluorescent dye DiOC(2)(3) in the presence and absence of zosuquidar, and dye accumulation measured by flow cytomet
A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia
β Scribed by Jeffrey E. Lancet; Maria R. Baer; George E. Duran; Alan F. List; Robert Fielding; John F. Marcelletti; Pratik S. Multani; Branimir I. Sikic
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 195 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0145-2126
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