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A Phase I Trial of Cisplatin Plus Decitabine, a New DNA-Hypomethylating Agent, in Patients with Advanced Solid Tumors and a Follow-Up Early Phase II Evaluation in Patients with Inoperable Non-Small Cell Lung Cancer

✍ Scribed by G. Schwartsmann; H. Schunemann; C.N.F. Gorini; A.F. Ferreira Filho; C. Garbino; G. Sabini; I. Muse; L DiLeone; D.R. Mans


Book ID
110234872
Publisher
Springer US
Year
2000
Tongue
English
Weight
76 KB
Volume
18
Category
Article
ISSN
0167-6997

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A phase II trial of oral tegafur and ura
✍ Yukito Ichinose; Nobuko Takanashi; Tokujiro Yano; Hiroshi Asoh; Hideki Yokoyama; πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 391 KB πŸ‘ 2 views

## Background: The combination of uracil and tegafur in a 4:1 molar concentration (uft) has a greater antitumor activity than 5-fluorouracil (5-fu) and tegafur. because the combination of 5-fu and cisplatin has been proven to have a synergistic antitumor effect in many experimental and clinical stu