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A phase I study of weekly oxaliplatin (OXA) + continous infusion (CI) fluorouracil (FU) in patients with advanced colorectal cancer(CCR)

✍ Scribed by A. Aschele; S. Lonardi; L. Sartor; A. Perin; V. Chiarion Sileni; G. Artioli; S. Monfardini


Book ID
117658127
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
192 KB
Volume
37
Category
Article
ISSN
0959-8049

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Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer