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A phase I study of nolatrexed dihydrochloride in children with advanced cancer. A United Kingdom Children’s Cancer Study Group Investigation

✍ Scribed by Estlin, E J; Pinkerton, C R; Lewis, I J; Lashford, L; McDowell, H; Morland, B; Kohler, J; Newell, D R; Boddy, A V; Taylor, G A


Book ID
111724431
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
132 KB
Volume
84
Category
Article
ISSN
0007-0920

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Phase I/II study of bisantrene in childh
✍ Movassaghi, Nasser ;Krivit, William A. ;Krailo, Mark D. ;Hammond, G. Denman 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB

A phase I/II study of bisantrene using a 3-week schedule was undertaken in 171 children with refractory leukemias and solid tumors. The doses ranged from 190 to 430 mg/m2. The maximum tolerated dose for children with solid tumors and acute leukemias was 280 mg/m2 and 360 mg/m2 every 3 weeks, respect