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A phase I study of liposomal-encapsulated docetaxel (LE-DT) in patients with advanced solid tumor malignancies

✍ Scribed by John F. Deeken, Rebecca Slack, Glen J. Weiss…


Book ID
120776591
Publisher
Springer
Year
2012
Tongue
English
Weight
216 KB
Volume
71
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and docetaxel have single‐agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with ad