A phase I study of ifosfamide with mesna given daily for 3 consecutive days to children with malignant solid tumors
โ Scribed by Charles B. Pratt; William H. Meyer; Edwin C. Douglass; Laura Bowman; Judith Wilimas; Judith Ochs; Neyssa Marina; Loraine Avery; Elizabeth I. Thompson
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 431 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. Raltitrexed is a novel thymidylate synthase inhibitor with single agent activity in colorectal, nonsmall cell lung, and breast carcinomas. The recommended Phase II dose of raltitrexed administered as a single agent is 3 mg/m 2 every 3 weeks. Paclitaxel also has a broad spectrum of a
## Background: This phase i trial was developed to determine the safety, biologic activity, and effects on hematopoietic recovery of pixy321 following ifosfamide, carboplatin, and etoposide chemotherapy for children with recurrent or refractory solid tumors. ## Methods: Children (age < 22 years a