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A Phase I Study of High-dose BCNU, Etoposide and Escalating-dose Thiotepa (BTE) with Hematopoietic Progenitor Cell Support in Adults with Recurrent and High-risk Brain Tumors

✍ Scribed by Kyriakos P. Papadopoulos; Casilda Balmaceda; Michael Fetell; Elizabeth Kaufman; Linda T. Vahdat; Jeffrey Bruce; Michael Sisti; Steven Isaacson; Robert De LaPaz; David G. Savage; Andrea Troxel; Karen H. Antman; Charles S. Hesdorffer


Book ID
110234913
Publisher
Springer US
Year
1999
Tongue
English
Weight
49 KB
Volume
44
Category
Article
ISSN
0167-594X

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Phase I study of high-dose thiotepa with
✍ Pession, Andrea; Prete, Arcangelo; Locatelli, Franco; Bella, Santiago; Melchiond πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 70 KB πŸ‘ 2 views

Background. The aim of this phase I study was to define the maximum tolerated dose (MTD) of thiotepa (TT), administered with busulfan (BU) 480 mg/m 2 and etoposide 2,400 mg/m 2 , followed by autologous bone marrow transplantation (ABMT) or peripheral blood stem cell transplantation (APBSCT) support