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A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer

✍ Scribed by Yukio Iwashita; Kouichirou Tahara; Shigeru Goto; Atsushi Sasaki; Seiichiro Kai; Masataka Seike; Chao-Long Chen; Katsunori Kawano; Seigo Kitano


Publisher
Springer-Verlag
Year
2003
Tongue
English
Weight
298 KB
Volume
52
Category
Article
ISSN
0340-7004

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Tumor cells transfected to express immunostimulatory cytokines, or admixed with similarly modified bystander cells, are able to induce immune responses against unmodified tumor cells in animal models. For treatment of human patients, a vaccine composed of autologous tumor cells and IL-2-secreting al