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A phase I study of a combination of anti-CD19 and anti-CD22 immunotoxins (Combotox) in adult patients with refractory B-lineage acute lymphoblastic leukaemia

✍ Scribed by John Schindler; Srikanth Gajavelli; Farhad Ravandi; YuMin Shen; Samir Parekh; Ira Braunchweig; Stefan Barta; Victor Ghetie; Ellen Vitetta; Amit Verma


Book ID
108677339
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
134 KB
Volume
154
Category
Article
ISSN
0007-1048

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Lineage specific treatment of adult pati
✍ Ted P. Szatrowski; Richard K. Dodge; Carol Reynolds; Carol A. Westbrook; Stanley πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 111 KB

## Background: Anti-b4-blocked ricin is an immunotoxin comprised of an anti-cd19 murine monoclonal antibody (b4) conjugated to blocked ricin, which has cytotoxic activity in patients with lymphoid malignancies. ## Methods: Adults with untreated acute lymphoblastic leukemia (all) were treated with