𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A phase I study including pharmacokinetics of polyethylene glycol conjugated interleukin-2

✍ Scribed by Meyers, Frederick J; Paradise, Carolyn; Scudder, Sidney A; Goodman, Gary; Konrad, Michael

Book ID
109845013
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
515 KB
Volume
49
Category
Article
ISSN
0009-9236

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A Phase I–II trial of polyethylene glyco
A Phase I–II trial of polyethylene glycol-conjugated L-asparaginase in patients with multiple myeloma
✍ Neeraj R. Agrawal; Ronald M. Bukowski; Lisa A. Rybicki; Joanne Kurtzberg; Lewis πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 77 KB

## Abstract ## BACKGROUND Multiple myeloma remains an incurable disease. New agents are needed to improve therapy for patients with this disease. Previous investigators evaluated in vitro sensitivity of myeloma cells to polyethylene glycol‐conjugated L‐asparaginase (PEG‐L‐asparaginase) using the h

Phase I and pharmacokinetic study of a s
Phase I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors : The relation between pharmacokinetic property and toxicity
✍ Ruey-Long Hong; Yun-Long Tseng πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 99 KB πŸ‘ 2 views

## BACKGROUND. Compared with free drug, sterically stabilized liposomal drug has prolonged circulation time and, thereby, higher tumor selectivity and antitumor activity. The stability in plasma is an important consideration in the formulation of clinically useful liposomal drug. A Phase I study o

A phase I study of subcutaneous recombin
A phase I study of subcutaneous recombinant interleukin-2 and interferon alfa-2a
✍ Mark J. Ratain; Edwin R. Priest; Linda Janisch; Nicholas J. Vogelzang πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 495 KB πŸ‘ 2 views

Background. Both recombinant in1 erferon alfa and interleukin-2 (IL-2) have been shown to lave some activity as single agents in metastatic renal cj !I1 cancer (RCC), although their activity is minimal in mo -e common solid tumors. Recent preclinical studies hav ? suggested that the combination of t