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A phase I pharmacokinetic study of hypoxic abdominal stop-flow perfusion with gemcitabine in patients with advanced pancreatic cancer and refractory malignant ascites

✍ Scribed by Andrea Kuemmerle; Laurent A. Decosterd; Thierry Buclin; Danielle Liénard; Roger Stupp; Pierre-Guy Chassot; François Mosimann; Ferdy Lejeune


Publisher
Springer
Year
2008
Tongue
English
Weight
523 KB
Volume
63
Category
Article
ISSN
0344-5704

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A phase 1 study of fixed dose rate gemci
✍ Weijing Sun; Maureen R. Hewitt; Marry R. Theobald; Diane Hershock; Daniel G. Hal 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 106 KB 👁 2 views

## Abstract ## BACKGROUND. The combination of a fixed dose rate (FDR) infusion of gemcitabine and irinotecan may have a synergistic effect in the treatment of patients with advanced and metastatic pancreatic and biliary cancer. The current study was conducted to determine the dose‐limiting toxicit