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A phase I dose escalation study of oral bexarotene in combination with intravenous decitabine in patients with AML

✍ Scribed by Welch, John S.; Niu, Haixia; Uy, Geoffrey L.; Westervelt, Peter; Abboud, Camille N.; Vij, Ravi; Stockerl-Goldstein, Keith E.; Jacoby, Meagan; Pusic, Iskra; Schroeder, Mark A.; Dipersio, John F.; Cashen, Amanda F.

Book ID: 126583764
Publisher: John Wiley and Sons
Year: 2014
Tongue: English
Weight: 654 KB
Volume: 89
Category: Article
ISSN: 0361-8609
DOI: 10.1002/ajh.23735

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## Abstract ## BACKGROUND Based on preclinical findings and on the clinical antitumor efficacy of sequential paclitaxel/topotecan and topotecan/etoposide, the authors sought to define the maximum tolerated doses (MTDs) and dose‐limiting toxicities (DLTs) associated with a sequential combination of