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A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours

โœ Scribed by Plummer, R; Wilson, R H; Calvert, H; Boddy, A V; Griffin, M; Sludden, J; Tilby, M J; Eatock, M; Pearson, D G; Ottley, C J


Book ID
109838845
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
326 KB
Volume
104
Category
Article
ISSN
0007-0920

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โœ J. Wagstaff; G. Chadwick; A. Howell; N. Thatcher; J. H. Scarffe; D. Crowther ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer ๐ŸŒ English โš– 503 KB

This study was designed to evaluate the clinical tolerance to multiple IM injections of rDNA-produced human alpha-2 interferon (IFN) (Schering-Plough 30500) in patients with solid tumours. IFN was administered in escalating IM doses in separate groups of patients daily for 14 days and then twice wee