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A phase 2 study of irinotecan, cisplatin, and simvastatin for untreated extensive-disease small cell lung cancer

✍ Scribed by Ji-Youn Han; Kun Young Lim; Sun Young Yu; Tak Yun; Heung Tae Kim; Jin Soo Lee


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
254 KB
Volume
117
Category
Article
ISSN
0008-543X

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Phase II trial of irinotecan, cisplatin
✍ Dean A. Fennell; Jeremy P.C. Steele; Jonathan Shamash; Sarah E. Slater; Michael πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 87 KB

## Abstract There is no standard therapy for relapsed small cell lung cancer (rSCLC). We evaluated the efficacy and toxicity of a new triplet consisting of irinotecan (100 mg/m^2^ Days 1 and 15 q28), cisplatin (40 mg/m^2^ Days 1 and 15 q28) and mitomycin (6 mg/m^2^ d1 q28) administered to a maximum

Phase II trial of irinotecan and cisplat
✍ Joo Hyuk Sohn; Yong Wha Moon; Chang Geol Lee; Gwi Eon Kim; Kyung Young Chung; Jo πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 91 KB πŸ‘ 2 views

## Abstract ## BACKGROUND. A Phase II trial of irinotecan and cisplatin (IP) with early concurrent radiotherapy was performed in limited‐disease small‐cell lung cancer (LD‐SCLC) to evaluate the efficacy and toxicity. ## METHODS. For untreated LD‐SCLC patients, irinotecan (60 mg/m^2^, Days 1, 8,