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A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma

โœ Scribed by Andrea L. Harzstark; Eric J. Small; Vivian K. Weinberg; Janine Sun; Charles J. Ryan; Amy M. Lin; Lawrence Fong; Dion R. Brocks; Jonathan E. Rosenberg


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
131 KB
Volume
117
Category
Article
ISSN
0008-543X

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Background. Twenty-nine patients with metastatic renal cell carcinoma (RCC) were treated with constantinfusion floxuridine (FUdR, Roche Laboratories, Nut-Methods. The initial dosage was 0.075 mg/kg/day for 14 days every 28 days and was increased or decreased by 0.025-mg/kg/day increments at each sub