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A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer

✍ Scribed by Henry Q. Xiong; William Plunkett; Robert Wolff; Min Du; Renato Lenzi; James L. Abbruzzese

Publisher
Springer
Year
2005
Tongue
English
Weight
223 KB
Volume
55
Category
Article
ISSN
0344-5704

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A pharmacological study of celecoxib and
A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer
✍ Henry Q. Xiong; William Plunkett; Robert Wolff; Min Du; Renato Lenzi; James L. A πŸ“‚ Article πŸ“… 2005 πŸ› Springer 🌐 English βš– 223 KB

## Purpose: To evaluate whether celecoxib alters the conversion of gemcitabine into its active metabolite, difluorodeoxycytidine triphosphate (dfdctp), in peripheral blood mononuclear cells (pbmcs). ## Methods: Patients with advanced pancreatic cancer who had not received chemotherapy and had acc

A phase 1 study of fixed dose rate gemci
A phase 1 study of fixed dose rate gemcitabine and irinotecan in patients with advanced pancreatic and biliary cancer
✍ Weijing Sun; Maureen R. Hewitt; Marry R. Theobald; Diane Hershock; Daniel G. Hal πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 106 KB πŸ‘ 2 views

## Abstract ## BACKGROUND. The combination of a fixed dose rate (FDR) infusion of gemcitabine and irinotecan may have a synergistic effect in the treatment of patients with advanced and metastatic pancreatic and biliary cancer. The current study was conducted to determine the dose‐limiting toxicit