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A pharmacological assessment of opioid-induced respiratory depression and potential antagonisn by naltrexone

✍ Scribed by Iacono, Giuseppina; Bell, Rosonald; Norton, Kevin


Book ID
121914920
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
55 KB
Volume
68
Category
Article
ISSN
1056-8719

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Miconazole, at 0.2 Β΅M, decreased, by two orders of magnitude, the specific mutation rate of Saccharomyces cerevisiae to respiratory-deficient mutants (petites), which had been induced at either 37 Β°C or 39 Β°C. Identical concentrations of ketoconazole did not change the mutation rate. The results fit