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A pharmacokinetic study of ethanol inhibition of micronuclei induction by urethane in mouse bone marrow erythrocytes

✍ Scribed by Wai Nang Choy; William Black; George Mandakas; Elmer J. Mirro; Hugh E. Black

Book ID
119094050
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
743 KB
Volume
341
Category
Article
ISSN
0165-1218

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πŸ“œ SIMILAR VOLUMES

Application of pharmacokinetic/pharmacod
Application of pharmacokinetic/pharmacodynamic and stochastic modelling to 6-mercaptopurine micronucleus induction in mouse bone marrow erythrocytes
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## Abstract This study investigates the kinetics of bone marrow micronucleated polychromatic erythrocytes and some mechanistic aspects of micronuclei induction using mathematical models. Female mice were administered a single intraperitoneal injection of the purine antagonist 6‐mercaptopurine at 50