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A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION

โœ Scribed by ARGENTI, DOMENICK; IRELAND, DENISE; HEALD, DONALD L.


Book ID
123357027
Publisher
Lippincott Williams and Wilkins
Year
2001
Tongue
English
Weight
79 KB
Volume
165
Category
Article
ISSN
0022-5347

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The single-dose pharmacokinetics and bioavailability of three ketoconazole formulations were evaluated using HPLC in five healthy human volunteers and six male mongrel dogs. The human volunteers received 400 mg PO of ketoconazole as tablet (Ktab) and solution (K-,) formulations. The dogs received 40