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A pharmacogenetic study of polymorphisms in interferon pathway genes and response to interferon-α treatment in chronic hepatitis B patients

✍ Scribed by Xiaopan Wu; Xilin Zhu; Shuying Zhu; Jingyun Li; Juan Ma; Zhuo Li; Hui Li; Ying Liu

Book ID
113458126
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
152 KB
Volume
83
Category
Article
ISSN
0166-3542

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Interferon alfa (IFN-a) therapy remains a mainstay of treatment in active hepatitis B. However, sustained remission rates remain relatively low, and the search for factors important for response to therapy continues. Our study aimed to identify the host single nucleotide polymorphism (SNPs) that pre