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A Pharmacodynamically Responsive Model of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Transfer Between Liver and Fat at Low and High Doses

✍ Scribed by W.L. Roth; S. Ernst; L.W.D. Weber; L. Kerecsen; K.K. Rozman


Book ID
118771243
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
814 KB
Volume
127
Category
Article
ISSN
0041-008X

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## Abstract The induction response of cytochrome P‐450‐dependent enzyme activities to a single low (5 nmol/kg) or high (50 nmol/kg, intraperitoneal [ip] dose of TCDD was examined in liver and lung homogenates over a 12‐week time course in an outbred, Ah‐responsive strain of mice (National Institute