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A petite mitochondrial DNA segment arising in exceptionally high frequency in a mit− mutant of Saccharomyces cerevisiae

✍ Scribed by Christopher G. Bingham; Phillip Nagley

Book ID
119119199
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
1006 KB
Volume
740
Category
Article
ISSN
0167-4781

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✍ Paul Chambers; Elliot Gingold 📂 Article 📅 1986 🏛 Springer-Verlag 🌐 English ⚖ 726 KB

Work in recent years has produced indirect evidence to support the view that the phenomenon of suppressiveness in yeast is the result of the ability of the petite mtDNA to out-replicate the wild-type genome. We have developed a method, based on fluorography of gels containing restriction fragments o