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A Peptide Motif from the Second Fibronectin Module of the Neural Cell Adhesion Molecule, NCAM, NLIKQDDGGSPIRHY, is a Binding Site for the FGF Receptor

✍ Scribed by Jacob Jacobsen; Vladislav Kiselyov; Elisabeth Bock; Vladimir Berezin

Publisher: Springer
Year: 2008
Tongue: English
Weight: 472 KB
Volume: 33
Category: Article
ISSN: 0364-3190
DOI: 10.1007/s11064-008-9680-2

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## Abstract The neural cell adhesion molecule (NCAM) plays a pivotal role in neural development, regeneration, and plasticity. NCAM mediates adhesion and subsequent signal transduction through NCAM–NCAM binding. Recently, a peptide ligand termed P2 corresponding to a 12‐amino‐acid sequence in the F