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A peptide fragment of type II collagen induces the OA phenotype

✍ Scribed by P. Chan; C. Wu


Book ID
116729458
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
56 KB
Volume
25
Category
Article
ISSN
0945-053X

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A fibronectin fragment induces type II c
✍ Tadashi Yasuda; A. Robin Poole πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 279 KB

Objective. To examine the effects of a fibronectin (FN) fragment containing the COOH-terminal heparinbinding domain (HBFN-f) on chondrocyte-mediated type II collagen (CII) cleavage by collagenase and proteoglycan (PG) degradation in articular cartilage in explant culture. Methods. Intact FN or HBFN-