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A peptide derived from melanocytic protein gp100 and presented by HLA-B35 is recognized by autologous cytolytic T lymphocytes on melanoma cells

✍ Scribed by N. Vigneron; A. Ooms; S. Morel; W. Ma; G. Degiovanni; B.J. Van den Eynde


Book ID
110892097
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
120 KB
Volume
65
Category
Article
ISSN
0001-2815

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## Abstract The human tyrosinase gene has been reported previously to code for two distinct antigens recognized on HLA‐A2 melanoma cells by autologous cytolytic T lymphocytes (CTL). By stimulating lymphocytes of melanoma patient MZ2 with a subclone of the tumor cell line of this patient, we obtaine