Two contrasting cases of chronic refractory pure red cell aplasia (PRCA) responsive to a commercial preparation of horse antihuman thymocyte globulin (ATG) are reported. Both cases were refractory to trials of cyclophosphamide, corticosteroids, and plasmapheresis. One patient developed a reticulocyt
โฆ LIBER โฆ
A PEDIATRIC CASE OF PURE RED CELL APLASIA: SUCCESSFUL TREATMENT WITH ANTI-LYMPHOCYTE GLOBULIN AND CORRELATION WITH IN VITRO T CELL-MEDIATED INHIBITION OF ERYTHROPOIESIS
โ Scribed by Anna Corcione; Mirella Pasino; A. Claudio Molinari; Maura Acquila; Patrizia Marchese; Pier Giorgio Mori
- Book ID
- 114712558
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 227 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0007-1048
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Pure red cell aplasia (PRCA) is an unusual complication of chronic lymphoproliferative disorders. A patient with T-cell chronic lymphocytic leukemia (T-CLL) had severe anemia and neutropenia. Initial in vitro studies demonstrated no evidence of T-cell suppression of erythropoiesis. Sequential bone m