Huntington disease (HD) is an autosomal dominant neurodegenerative disorder associated with expansions of an unstable CAG trinucleotide repeat in exon 1 of the IT15 gene. In normal individuals, IT15 contains up to 35 CAG repeats, while in affected the repeat length is >36. Polymerase chain reaction
β¦ LIBER β¦
A PCR method for accurate assessment of trinucleotide repeat expansion in Huntington disease
β Scribed by Goldberg, Y.Paul; Andrew, Susan E.; Clarke, Lorne A.; Hayden, Michael R.
- Book ID
- 121500294
- Publisher
- Oxford University Press
- Year
- 1993
- Tongue
- English
- Weight
- 687 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0964-6906
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