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A patient with infantile spasms and low homovanillic acid levels in cerebrospinal fluid:l-dopa dependent seizures?

✍ Scribed by H. Sugie; Y. Sugie; N. Kato; Y. Fukuyama

Publisher: Springer
Year: 1989
Tongue: English
Weight: 221 KB
Volume: 148
Category: Article
ISSN: 0340-6997
DOI: 10.1007/bf00441530

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✦ Synopsis

We report a 3-month-old female with infantile spasms that responded transiently to pyridoxine and permanently to oral L-dopa. Initial CSF levels of homovanillic acid were low, suggesting disturbed turnover of dopamine. These findings suggest that disturbed brain monoamine metabolism may be causally related to infantile spasms.