A Paradigm for Cancer Treatment Using the Retinoblastoma Gene in a Mouse Model
β Scribed by ALEXANDER YU. NIKITIN; DANIEL J. RILEY; WEN-HWA LEE
- Book ID
- 111395727
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 682 KB
- Volume
- 886
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We have critically examined the nude mouse model for human retinoblastoma to determine whether or not characteristics found in the parent tumor are retained in the mouse. We have demonstrated that most tumors grown in the anterior chamber of the nude mouse maintain a similar karyotype,
In several ocular and nonocular cancer types, including familial and sporadic retinoblastoma, osteosarcoma, small cell lung cancer (SCLC), breast cancer, prostate cancer, and others, frequent loss or inactivation of the retinoblastoma tumor suppressor gene (Rb7) on chromosome 13q14.2 is associated w