To study the effect of methadone h-eatment in reducing multiple drug use, say heroin and benzodiazepines while controlling for their possible interaction, we analyse the results of urine drug screens from patients in treatment at a Sydney clinic in 1986. Weekly tests are either positive or negative
A pairwise likelihood approach to analyzing correlated binary data
โ Scribed by Anthony Y.C. Kuk; David J. Nott
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 85 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0167-7152
No coin nor oath required. For personal study only.
โฆ Synopsis
The method of pairwise likelihood is investigated for analyzing clustered or longitudinal binary data. The pairwise likelihood is a product of bivariate likelihoods for within cluster pairs of observations, and its maximizer is the maximum pairwise likelihood estimator. We discuss the computational advantages of pairwise likelihood relative to competing approaches, present some e ciency calculations and argue that when cluster sizes are unequal a weighted pairwise likelihood should be used for the marginal regression parameters, whereas the unweighted pairwise likelihood should be used for the association parameters.
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To obtain the correlation dimension and entropy from an experimental time series we derive estimators for these quantities together with expressions for their variances using a maximum likelihood approach. The validity of these expressions is supported by Monte Carlo simulations. We illustrate the u