𝔖 Bobbio Scriptorium
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A One-Step Synthesis of Squalene from Farnesol under Prebiotic Conditions

✍ Scribed by Dr. Gérard Teller; Prof. Dr. Yoichi Nakatani; Prof. Dr. Guy Ourisson; Dr. Martin Keller; Dipl.-Biol. Doris Hafenbradl; Prof. Dr. Karl O. Stetter

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
376 KB
Volume
34
Category
Article
ISSN
0044-8249

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## Abstract A cascade of two enzymatic transformations is employed in a one‐pot synthesis of cephalexin. The nitrile hydratase (from __R. rhodochrous__ MAWE)‐catalyzed hydration of D‐phenylglycine nitrile to the corresponding amide was combined with the penicillin G acylase (penicillin amidohydrola