A one-pot, efficient, and odorless synthesis of symmetrical disulfides using organic halides and thiourea in the presence of manganese dioxide and wet polyethylene glycol (PEG-200)

✍ Scribed by Habib Firouzabadi; Nasser Iranpoor; Mohammad Abbasi

• Publisher: Elsevier Science
• Year: 2010
• Tongue: French
• Weight: 158 KB
• Volume: 51
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/j.tetlet.2009.11.060

✦ Synopsis

Primary, secondary, tertiary, allylic, and benzylic halides are converted efficiently into symmetric disulfides in high yields using thiourea as the sulfur atom source. The reactions are odorless and are performed at 30-35 °C in wet PEG-200 using MnO 2 as an oxidant.