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A novel viral homologue of Bcl-2 and Ced-9

โœ Scribed by Christopher A. Smith


Book ID
114322389
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
184 KB
Volume
5
Category
Article
ISSN
0962-8924

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BCL-2, a novel regulator of apoptosis
โœ Julie R. Park; David M. Hockenbery ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 573 KB

The bcl-2 gene has a unique function among mammalian oncogenes as a negative regulator of apoptosis. Its expression pattern in embryonic and adult tissues is consistent with a role in maintaining in vivo survival of specific cell types. The biochemical function of bcl-2 is unknown, but its localiza