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✦   LIBER   ✦

A novel tumour model system for the study of long-term protective immunity and immune T cell memory

✍ Scribed by Yolanda D Mahnke; Volker Schirrmacher

Book ID
114008245
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
476 KB
Volume
221
Category
Article
ISSN
0008-8749

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## Abstract Evidence is presented for the existence of immune T lymphocytes which have protective activity __in vivo__ against the lethal effects of a metastasizing tumor. ESb, the metastasizing tumor cell line of our model system, which is highly malignant in syngeneic DBA/2 mice, can be rejected

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## Abstract In an attempt to analyze mechanisms of immunity against tumor metastases, protective anti‐tumor immunity __in vivo__ was compared with cytotoxic T‐cell activity __in vitro__ in a well‐defined syngeneic tumor model system. The system consists of a chemically induced parental tumor cell l