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A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma

✍ Scribed by Lin-wei Li; Yuan-yuan Li; Xiao-yan Li; Chun-peng Zhang; Yun Zhou; Shih-Hsin Lu

Book ID: 115010400
Publisher: BioMed Central
Year: 2011
Tongue: English
Weight: 608 KB
Volume: 11
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-11-52

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## Abstract The ECRG4 gene was initially identified and cloned in our laboratory from human normal esophageal epithelium (GenBank accession no. AF325503). We revealed the expression of ECRG4 protein was downregulated in 68.5% (89/130) ESCC samples using tissue microarray. The low ECRG4 protein expr