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A novel thermosensitive polymer with pH-dependent degradation for drug delivery

โœ Scribed by V.K. Garripelli; J.-K. Kim; R. Namgung; W.J. Kim; M.A. Repka; S. Jo


Book ID
108050394
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
811 KB
Volume
6
Category
Article
ISSN
1742-7061

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Novel salicylazo polymers for colon drug
โœ Sigal Saphier; Yishai Karton ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 184 KB

Novel azo polymers were prepared for colonic drug delivery with a release mechanism based on structural features of azo derivatives designed for rapid bacterial degradation leading to soluble polymers. Two Salicylazo derivatives were prepared and conjugated as side chains at different ratios to meth