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A Novel Therapy for Myasthenia Gravis by Reducing the Endocytosis of Acetylcholine Receptors

โœ Scribed by RALPH W. KUNCL; ILAN WITTSTEIN; ROBERT N. ADAMS; WINSTON W. WIGGINS; ORLANDO AVILA; ALAN PESTRONK; KEVIN McINTOSH; DONNA LUCAS; SHARI DESILVA; MOHAMED LEHAR; DANIEL B. DRACHMAN


Book ID
119868530
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
269 KB
Volume
681
Category
Article
ISSN
0890-6564

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Myasthenia gravis (MG) is a neuromuscular disorder of man caused by a humoral response to the acetylcholine receptor (AChR). Most of the antibodies in MG and in experimental autoimmune myasthenia gravis (EAMG) are directed to the extracellular portion of the AChR alpha subunit, and within it, primar