A novel synthetic route to phenyl-substituted pyridines synthesis of [1]benzopyrano[4,3-b]pyridines [1]benzothiopyrano[4,3-b]pyridines and pyrido[3,2-b] [1,4]benzothiazines(1-azaphenothiazines).
✍ Scribed by D.V. Tyndall; T. Al Nakib; M.J. Meegan
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 36 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
## Abstract The condensation of 4‐hydroxy‐6‐methyl‐2__H__‐pyran‐2‐one and substituted 2‐hydroxybenzaldehydes with ammonium acetate gave the title heterocycles. Synthesis of 1,5‐dihydro‐2‐methyl‐4__H__‐[1]naphtho‐[1′,2′:5,6]pyrano[4,3‐__b__]‐pyridine‐4,5‐dione is also described. A reaction mechanism
## Abstract The title compounds 5a‐c and 7a‐m have been prepared by Vilsmeier formylation of 4‐aminocoumarins 1 yielding aldehydes 2, and subsequent condensation of 2 with C‐H acids in the presence of piperidine. This condensation probably proceeds via the intermediate ylidenemalonic esters 4. By m