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A novel synthesis of substituted naphthalenes via Claisen rearrangement and RCM reaction

โœ Scribed by Keng-Shiang Huang; Eng-Chi Wang


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
69 KB
Volume
42
Category
Article
ISSN
0040-4039

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A novel synthesis of indole derivatives
โœ B.S. Thyagarajan; J.B. Hillard; K.V. Reddy; K.C. Majumdar ๐Ÿ“‚ Article ๐Ÿ“… 1974 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 149 KB

We wish to report a facile thermal rearrangement of an N-aryl propynylamine oxide to an indole. The present study, to our knowledge, is the first report of such a rearrangement. Compound 1 (89.5%; m.p. 76-77)\* was prepared by the condensation of l-(4-chlorophenoxy)-4chloro-2-butyne3 with two moles