A novel synthesis of nocardicins and their analogues

✍ Scribed by T. Kamiya; T. Oku; O. Nakaguchi; H. Takeno; M. Hashimoto

• Publisher: Elsevier Science
• Year: 1978
• Tongue: French
• Weight: 238 KB
• Volume: 19
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)85827-5

✦ Synopsis

Nocardicins, represented by nocardicin A (&), are a new class of 8-lactam antibiotics which show an activity against gram-negative bacteria including Pseudomonas and Proteus'. As part of have developed an efficient procedure tam ring system and herein report the ANA, 2) which is the basic nucleus of method is also of general utility for pounds. our synthetic program to nocardicins, we for the preparation of a monocyclic f3-lac-