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A novel synthesis of disubstituted ureas using titanium(IV) isopropoxide and sodium borohydride

✍ Scribed by Joseph D. Armstrong III; Chad N. Wolfe; Jennifer L. Keller; Joseph Lynch; M. Bhupathy; R.P. Volante; Robert J. De Vita

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 168 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00149-4

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✦ Synopsis

This paper describes a high yield preparation of unsymmetrically disubstituted ureas by a titanium(IV) isopropoxide /sodium borohydride mediated reductive amidation of aromatic aldehydes with monosubstituted ureas.

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