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A novel synthesis of 4′-thionucleosides and a potential stereospecific route to pyrimidine nucleosides
✍ Scribed by J.Allen Miller; Ashley W Pugh; G.Mustafa Ullah; Clare Gutteridge
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 103 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A new route to the synthesis of pyrazole and pyrimidine C-nucleosides, which involves as the key step a metal promoted reaction of ~-D-ribofuranosyl ketoesters with alkyl cyanoformates is described. 2,3,5-Tri-O-benzoyl-~-D-ribofuranosyl cyanide I reacts with ct-bromoesters, in the presence of zinc d
A new route to the synthesis of pyrazole and pyrimidine C-nucleosides, involving as the key step a metal catalysed reaction of [3-D-ribofuranosyl ketoesters with alkyl cyanoformates, is described. 2,3,5-Tri-O-benzoyl-13-D-ribofuranosyl cyanide (1) reacts with ¢t-bromoesters, in the presence of zinc