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A Novel Synthesis of 2-Azabicyclo[2.1.1]hexane from Pyridine

✍ Scribed by Krow, Grant R.; Lee, Yoon B.; Lester, Walden S.; Christian, Hermona; Shaw, Donald A.; Yuan, Jing

Book ID: 121224877
Publisher: American Chemical Society
Year: 1998
Tongue: English
Weight: 64 KB
Volume: 63
Category: Article
ISSN: 0022-3263
DOI: 10.1021/jo9808472

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## Abstract The reactions of 3‐phenyl‐1‐azabicyclo[1.1.0]butane (**4**) with dimethyl dicyanofumarate ((__E__)‐**8**) and dimethyl dicyanomaleate ((__Z__)‐**8**) lead to the same mixture of __cis__‐ and __trans__‐4‐phenyl‐1‐azabicyclo[2.1.1]hexane 2,3‐dicarboxylates (__cis__‐**11** and __trans__‐**